Fatty Acid Ratios as Parameters to Discriminate Between Normal and Tumoral Cells and Compare Drug Treatments in Cancer Cells

targeted drug delivery to cancer stem cells by hyaluronic acid-based drug conjugates: synthesis and characterization

EFFECT OF CARUM CARVI ESSENTIAL OIL NANOEMULSION ON TUBO CANCER CELLS AND L929 NORMAL CELLS AND EVALUATION OF ANTIOXIDANT ACTIVITY

Background & Aims: Free radicals are one of the causes of cancer. In case of the disease, some cells of the body progress to the surrounding tissues and divide without stopping. The use of natural antioxidants plays a positive role in maintaining the health. Cancer and the presence of free radicals in the body motivated researchers to study substances that may eliminate them. The purpose of thi...

Expression pattern of fatty acid-binding proteins in human normal and cancer prostate cells and tissues.

PURPOSE Fatty acid-binding protein (FABP) expression patterns were evaluated as potential markers and therapeutic targets for prostate cancer. EXPERIMENTAL DESIGN FABP expression levels were determined by reverse transcription-PCR in cultured prostate normal and tumor cells and in human biopsy samples. Regulation of cellular processes was examined using FABP antisense constructs. RESULTS Pr...

Chemotherapeutic treatments involving drug resistance and level of normal cells as a criterion of toxicity.

A system of differential equations for the control of tumor cells growth in a cycle nonspecific chemotherapy is presented. Drug resistance and toxicity conveyed through the level of normal cells are taken into account in a class of optimal control problems. Alternative treatments for the exponential tumor growth are set forth for cases where optimal treatments are not available.

Atorvastatin Sensitizes Breast and Lung Cancer Cells to Ionizing Radiation

Tumour cells may be resistant to radiotherapy that results in unsuccessful cancer treatment in patients. The aim of this study was to evaluate the sensitizing effect of atorvastatin (ATV) on breast cancer (MDA-MB-231) and non-small cell lung cancer (A-549) cells following exposure to ionizing radiation (IR). These cells were treated with ATV and exposed to X-ray at dose 4 Gy. The radiosensitizi...